ONCC Practice Tests (OCN - Treatment Modalities) 2025/2026 Questions & Answers | 100% Correct | Verified

A patient demonstrates an adequate understanding of the teaching provided regarding chemotherapy
and myelosuppression by stating: "Myelosuppression is:
a potential side effect of many cancer treatments."
unintentional prior to a bone marrow transplant."
when laboratory values show an elevation in the white blood cell count."
the overreaction of the body's immune system to a medication." - ✔✔a potential side effect of many
cancer treatments."
Answer: Chemotherapy will decrease the response by the immune system by causing neutropenia,
anemia, and thrombocytopenia, collectively known as myelosuppression.
Reference: Polovich, M., Olsen, M., & LeFebvre, K. (Eds.). (2014). Chemotherapy and biotherapy
guidelines and recommendations for practice (4th ed.). Pittsburgh, PA: Oncology Nursing Society, p. 171.
Alkylating agents exert their effects by:
binding to DNA strands, preventing DNA replication and cell division.
causing the release of toxic free radicals inside the cell, triggering cell apoptosis.
attaching to CD52 on the surface of B and T cells, resulting in antibody-dependent lysis.
disrupting folate-dependent metabolic processes essential for cell replication. - ✔✔binding to DNA
strands, preventing DNA replication and cell division.
Answer: Alkalyting agents break the DNA helix strand and interfere with DNA replication.