NUR 354 Exam 2
What drug class do furosemide and bumetanide fall under?
loop diuretics
what is the pharmacological action of loop diuretics?
- block reabsorption of sodium, chloride, and water in the loop of Henle
Which diuretic class still works well in kidney impairment?
loop diuretics
What are the therapeutic uses associated with loop diuretics?
- reduce edema from HF, cirrhosis, and renal failure
- can be used to temporarily treat hypertension from FVE
What are the drug interactions associated with loop diuretics?
- hypokalemia risk: may cause dysrhythmias with digoxin and cardiac glycosides (heart
failure meds)
- caution with meds that are nephrotoxic or ototoxic like opioids and amino-glycoside
antibiotics
- may counteract insulin and cause hyperglycemia due to increased blood concentration
What are the food interactions associated with loop diuretics?
- hawthorn= hypotension
- ginseng and high sodium reduce effectiveness
What side effects are associated with loop diuretics?
- hypokalemia and other electrolyte imbalances
- dehydration
- hypotension
- hypovolemia
What adverse effects are associated with loop diuretics?
- ototoxicity: tinitus, vertigo, nausea
- hyperglycemia
- hyperuricemia
- increased LDL and decreased HDL
What are some nursing interventions for loop diuretics?
- obtain baseline data: vitals, i's&o's, amount and placement of edema, lung sounds,
skin turgor, mucus membrane assessment
- daily weights at same time each day