NSG 124 Pharmacology READINESS EXAM GUIDE Q & S 2025/2026

1. Which of the following is primarily responsible for the
metabolism of drugs?
 - A) Liver
 - B) Kidney
 - C) Intestines
 - D) Lungs
 Correct Answer: A) Liver
 Rationale: The liver contains enzymes that metabolize
drugs, particularly through the cytochrome P450 system.
2. Which of the following pharmacokinetic processes
refers to the movement of drugs into the bloodstream?
 - A) Distribution
 - B) Absorption
 - C) Metabolism
 - D) Excretion
 Correct Answer: B) Absorption
 Rationale: Absorption is the process through which
drugs enter the systemic circulation.
3. What is the term for the dosage of a drug that produces
a therapeutic effect in 50% of the population?
 - A) LD50
 - B) ED50
 - C) TD50
 - D) IC50
 Correct Answer: B) ED50
 Rationale: The ED50 (effective dose 50) is the dose
required to elicit a therapeutic response in half of a tested
population.
4. Which of the following drug routes would avoid first